Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623952 | 0.73 | ALDH1A1 (0.37) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL18623953 | 0.73 | SMN1; SMN2 (0.35) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL18179775 | 0.69 | MEN1 (0.43) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL18606132 | 0.67 | ALDH1A1 (0.43) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL18623960 | 0.65 | ALDH1A1 (0.34) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL28333326 | 0.63 | ALDH1A1 (0.36) | MEN1KMT2AUSP2TSHRSMN1; SMN2 | |
| SCHEMBL2124307 | 0.62 | HTT (0.46) | MEN1KMT2AUSP2HTTTSHR | |
| SCHEMBL30712035 | 0.62 | MEN1 (0.47) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL30712039 | 0.62 | MEN1 (0.47) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL18623959 | 0.62 | MAPT (0.38) | MEN1KMT2AHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144315-B1 | ENZYME-SPECIFIC FLUORESCENT COMPOUND CAPABLE OF BEING RETAINED IN CELLS | UNIV TOKYO (JP) | 2022-07-06 | — | — | EP | disclosed |