SCHEMBL186243

SCHEMBL186243

C#Cc1ccc(F)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL31266623 0.97 HDAC8 (0.43)
SCHEMBL28074282 0.97 HDAC8 (0.43)
SCHEMBL713797 0.92 GRM5 (0.42)
SCHEMBL8531033 0.92 PYCR1 (0.41)
Methoxyamine SCHEMBL6659047 0.85 CA12 (0.39)
SCHEMBL28195044 0.85 CA12 (0.39)
SCHEMBL28871 0.83 HDAC8 (0.59)
SCHEMBL3892483 0.82 GRM5 (0.44)
SCHEMBL9133037 0.82 CA1 (0.55)
SCHEMBL13729097 0.82 SMN1; SMN2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2296 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059955-A Imidazo pyridone compound, photocatalysis continuous synthesis method and application thereof 南京工业大学 2026-05-19 CN claimed
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN claimed
CN-116606310-B Heterogeneous catalyst for catalyzing alkyne and B2Pin2Application in borohydride reaction 昆明理工大学 2025-05-23 CN claimed
CN-119771506-A Supported Cu-based nanocluster catalyst and application thereof 安徽大学 2025-04-08 CN claimed
CN-116102608-B Stigmasterol triazole derivative and preparation method and application thereof 郑州工程技术学院 2025-03-28 CN claimed
CN-119708067-A Carbazolyl-containing C≡N cyclometalated platinum (II) complex and preparation method and application thereof 新疆大学 2025-03-28 CN claimed
CN-119680640-A Alkyne selective hydrogenation catalyst with high activity and high selectivity and preparation method thereof 甬江实验室 2025-03-25 CN claimed
CN-119633864-A Method for preparing thiophene compound by using one-pot method through double-function catalyst and catalyst used by same 浙江大学 2025-03-18 CN claimed
CN-119608153-A Preparation method and hydrogenation application of Pd-Ru synergistic catalyst based on metal organic framework 聊城大学 2025-03-14 CN claimed
CN-115838382-B Synthesis method of beta-ketophosphorus oxide 惠州学院 2025-03-04 CN claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed
EP-0771196-B1 EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 1999-12-08 EP claimed
WO-1999029761-A2 POLY(ARYLENE ETHER) COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF ALLIEDSIGNAL INC. (US) 1999-06-17 WO claimed
EP-0827507-B1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM CA LTD (CA) 1999-06-16 EP claimed
EP-0854849-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1998-07-29 EP claimed
WO-1997010193-A1 ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF THE DOW CHEMICAL COMPANY (US) 1997-03-20 WO claimed
EP-0690855-B1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-12-18 EP claimed
EP-0328830-B1 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds OHMEDA PHARMA PROD (US) 1994-06-01 EP claimed
EP-0500409-A1 4-Pyrimidinone derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1992-08-26 EP claimed
EP-0177515-B1 3-AMINOPROPYLOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Louis, William John (AU) 1989-05-31 EP claimed