Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186243 | 0.85 | — | — | |
| SCHEMBL28074282 | 0.83 | HDAC8 (0.43) | CA12CA1CA2CA4CA9 | |
| Iodide SCHEMBL31266623 | 0.83 | HDAC8 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL27263162 | 0.80 | CES2 (0.43) | CA1CA2CA9CES2CES1 | |
| SCHEMBL8531033 | 0.78 | PYCR1 (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL713797 | 0.78 | GRM5 (0.42) | CA12CA1CA2CA4CA9 | |
| Phenylacetylene SCHEMBL27475394 | 0.76 | APP (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL28061276 | 0.75 | GRM5 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL566015 | 0.74 | LTA4H (0.53) | CA1CA2PTPN1ESR1CES2 | |
| SCHEMBL9133037 | 0.74 | CA1 (0.55) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107446127-A | Preparation method of modified thermosetting polyphenyl ether resin | 南亚塑胶工业股份有限公司 | 2017-12-08 | — | — | CN | disclosed |