Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186243 | 0.97 | — | — | |
| Iodide SCHEMBL31266623 | 0.94 | HDAC8 (0.43) | HDAC8CA1CA2CA9CA12 | |
| SCHEMBL713797 | 0.89 | GRM5 (0.42) | HDAC8CA1CA2CA9CA12 | |
| SCHEMBL8531033 | 0.89 | PYCR1 (0.41) | HDAC8CA1CA2CA9CA12 | |
| Methoxyamine SCHEMBL6659047 | 0.83 | CA12 (0.39) | HDAC8CA1CA2CA9CA12 | |
| SCHEMBL28195044 | 0.83 | CA12 (0.39) | HDAC8CA1CA2CA9CA12 | |
| SCHEMBL28871 | 0.80 | HDAC8 (0.59) | HDAC8CA1CA2CA9CA12 | |
| SCHEMBL9133037 | 0.79 | CA1 (0.55) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3892483 | 0.79 | GRM5 (0.44) | CA1CA2CA9CA12CA14 | |
| SCHEMBL13729097 | 0.79 | SMN1; SMN2 (0.46) | HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102881296-B | Optical data carrier records method and the optical data carrier of data | 通用电气公司 | 2016-07-06 | — | — | CN | claimed |
| CN-102881296-B | Optical data carrier records method and the optical data carrier of data | 通用电气公司 | 2016-07-06 | — | — | CN | disclosed |