SCHEMBL186246

SCHEMBL186246

NCC(=O)OC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
TDP1 Q9NUW8 5/20 0.48
TSHR P16473 5/20 0.48
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 4/20 0.47
MAPT P10636 4/20 0.47
POLB P06746 2/20 0.47
MAPK1 P28482 2/20 0.47
HIF1A Q16665 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2762547 0.98 LMNA (0.50) LMNAF2TDP1TSHRALDH1A1
SCHEMBL2762264 0.98 LMNA (0.50) LMNAF2TDP1TSHRALDH1A1
SCHEMBL29035467 0.93 ELANE (0.51) LMNAF2TDP1TSHRALDH1A1
SCHEMBL29382078 0.89 LOXL2 (0.45) LMNAF2TDP1TSHRALDH1A1
SCHEMBL28414959 0.86 LMNA (0.50) LMNAF2TDP1TSHRALDH1A1
SCHEMBL29381825 0.86 LOXL2 (0.47) LMNAF2TDP1ALDH1A1L3MBTL1
SCHEMBL29035397 0.86 SMN1; SMN2 (0.58) ALDH1A1KMT2AMAPTPARP10SMN1; SMN2
SCHEMBL28194586 0.83 LMNA (0.44) LMNAF2TDP1TSHRALDH1A1
SCHEMBL9318015 0.83 LMNA (0.56) LMNAF2TDP1TSHRALDH1A1
SCHEMBL2611692 0.83 TSHR (0.58) LMNAF2TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119220450-A Lactobacillus plantarum and application thereof 江苏卫岗乳品研究院有限公司 2024-12-31 CN claimed
CN-116018141-A Salt and crystal form containing indole derivatives, and preparation method and application thereof 上海翰森生物医药科技有限公司 2023-04-25 CN claimed
WO-2022105882-A1 SALT AND CRYSTAL FORM OF INDOLE-CONTAINING DERIVATIVE, AND PREPARATION METHODS THEREFOR AND APPLICATIONS THEREOF 上海翰森生物医药科技有限公司 2022-05-27 WO claimed
CN-110835523-B Emulsifying viscosity reducer for cold production of thick oil and preparation method thereof 中国石油化工股份有限公司 2022-02-15 CN claimed
CN-110835523-A Emulsifying viscosity reducer for cold production of thick oil and preparation method thereof 中国石油化工股份有限公司 2020-02-25 CN claimed
CN-107522627-B Preparation method of 5-aminolevulinic acid hydrochloride 台州职业技术学院 2019-12-13 CN claimed
CN-119220450-A Lactobacillus plantarum and application thereof 江苏卫岗乳品研究院有限公司 2024-12-31 CN disclosed
CN-118619931-A Aryl or heteroaryl derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2024-09-10 CN disclosed
CN-118420512-A Benzoyl glycine derivative, and preparation method and application thereof 中国药科大学 2024-08-02 CN disclosed
CN-118420512-A Benzoyl glycine derivative, and preparation method and application thereof 中国药科大学 2024-08-02 CN disclosed
CN-118420512-A Benzoyl glycine derivative, and preparation method and application thereof 中国药科大学 2024-08-02 CN disclosed
CN-116018141-A Salt and crystal form containing indole derivatives, and preparation method and application thereof 上海翰森生物医药科技有限公司 2023-04-25 CN disclosed
WO-2022105882-A1 SALT AND CRYSTAL FORM OF INDOLE-CONTAINING DERIVATIVE, AND PREPARATION METHODS THEREFOR AND APPLICATIONS THEREOF 上海翰森生物医药科技有限公司 2022-05-27 WO disclosed
US-4692459-A SULFUR CONTAINING AMINO ACID DERIVATIVES, ANGIOTENSIN INHIBITOR UNIVERSITY OF MIAMI (US) 1987-09-15 US disclosed
US-4690940-A Anti-hypertensive agents UNIVERSITY OF MIAMI (US) 1987-09-01 US disclosed
EP-0035383-B1 ANGIOTENSIN CONVERTING ENZYME INHIBITORS UNIVERSITY OF MIAMI (US) 1984-05-30 EP disclosed
US-4439449-A Medicament for diminution of oxalate development and excretion in urine DR. MADAUS & CO. (DE) 1984-03-27 US disclosed
EP-0035383-A1 Angiotensin converting enzyme inhibitors UNIVERSITY OF MIAMI (US) 1981-09-09 EP disclosed
US-4272516-A ADDING BENZYL ALCOHOL AS AN ACTIVATOR Societa Italo-Britannica-L. Manetti-H. Roberts Co. (IT) 1981-06-09 US disclosed
US-4191753-A Anti-hypertensive peptide analogs UNIVERSITY OF MIAMI (US) 1980-03-04 US disclosed