Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187797 | 0.86 | AKR1C3 (0.58) | SMN1; SMN2PARP10ERCC5FEN1ALDH1A1 | |
| SCHEMBL186246 | 0.86 | LMNA (0.52) | SMN1; SMN2PARP10ALDH1A1MAPTRAB9A | |
| SCHEMBL26119241 | 0.85 | MMP13 (0.50) | SMN1; SMN2PARP10ALDH1A1MAPTRAB9A | |
| SCHEMBL16174814 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2PARP10SRD5A2ERCC5FEN1 | |
| SCHEMBL2762264 | 0.84 | LMNA (0.50) | SMN1; SMN2PARP10ALDH1A1MAPTRAB9A | |
| SCHEMBL2762547 | 0.84 | LMNA (0.50) | SMN1; SMN2PARP10ALDH1A1MAPTRAB9A | |
| SCHEMBL6892695 | 0.84 | PARP10 (0.64) | SMN1; SMN2PARP10SRD5A2ERCC5FEN1 | |
| SCHEMBL29382078 | 0.84 | LOXL2 (0.45) | SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL29035467 | 0.83 | ELANE (0.51) | PARP10SRD5A2ALDH1A1MAPTRAB9A | |
| SCHEMBL28620841 | 0.82 | PARP10 (0.62) | SMN1; SMN2PARP10SRD5A2ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |