Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18624972 | 0.85 | TSHR (0.40) | FOLH1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL21711727 | 0.76 | MRGPRX4 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL25126172 | 0.75 | RXRA (0.59) | FOLH1RXRARXRBTP53TSHR | |
| SCHEMBL27831466 | 0.75 | TSHR (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18624971 | 0.74 | FOLH1 (0.50) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31469856 | 0.72 | CASP6 (0.54) | TSHR | |
| SCHEMBL28374522 | 0.71 | RARB (0.53) | FOLH1RXRARXRBTP53RARA | |
| SCHEMBL18100911 | 0.71 | SRD5A2 (0.42) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23906521 | 0.71 | KDM4E (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL14008691 | 0.70 | HDAC1 (0.41) | FOLH1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690920-B2 | General and direct method for preparing oligonucleotide-functionalized metal-organic framework nanoparticles | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | claimed |
| US-11690920-B2 | General and direct method for preparing oligonucleotide-functionalized metal-organic framework nanoparticles | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210236651-A1 | General and Direct Method for Preparing Oligonucleotide-Functionalized Metal-Organic Framework Nanoparticles | NORTHWESTERN UNIVERSITY | 2021-08-05 | — | — | US | disclosed |
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-3141263-A1 | METAL-ORGANIC FRAMEWORK/STIMULUS-RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | National University Corporation Hokkaido University (JP) | 2017-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | ORAI1, SARAF, TRPM8 | FOLH1 2971/4885HDAC3 2323/4885HDAC4 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.