Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191034 | 0.72 | CRHBP (0.39) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31290998 | 0.72 | CRHBP (0.39) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16875663 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4ERAB9AMEN1 | |
| SCHEMBL15550514 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL11522294 | 0.64 | BRD4 (0.59) | BRD4ALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL16875669 | 0.63 | MDM2 (0.42) | ALDH1A1KMT2ASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6108137 | 0.61 | SMN1; SMN2 (0.44) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11622461 | 0.60 | KMT2A (0.48) | BRD4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL31587599 | 0.60 | LMNA (0.42) | KMT2ALMNAMEN1NR3C1 | |
| SCHEMBL25359757 | 0.60 | CYP19A1 (0.58) | BRD4KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593125-B2 | Heterocyclic flavone derivatives, compositions, and methods related thereto | EMORY UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |