Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28960243 | 0.86 | ALOX15 (0.33) | CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL16699523 | 0.76 | CYP1A2 (0.42) | CYP1A2KDM4ELMNASMN1; SMN2ADRB2 | |
| SCHEMBL29134383 | 0.76 | CYP1A2 (0.42) | CYP1A2KDM4ELMNASMN1; SMN2ADRB2 | |
| SCHEMBL18625595 | 0.76 | LMNA (0.31) | CYP1A2KDM4ELMNASMN1; SMN2 | |
| SCHEMBL18341172 | 0.76 | LMNA (0.31) | CYP1A2KDM4ELMNASMN1; SMN2 | |
| SCHEMBL16699682 | 0.73 | LMNA (0.36) | CYP1A2KDM4ELMNASMN1; SMN2ADRB2 | |
| SCHEMBL28943606 | 0.72 | LMNA (0.33) | CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL28943607 | 0.72 | LMNA (0.33) | CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL25379497 | 0.71 | LMNA (0.32) | CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL31047801 | 0.71 | LMNA (0.32) | CYP1A2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598423-B2 | Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-21 | — | — | US | disclosed |