Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943607 | 0.85 | LMNA (0.33) | LMNAHSD17B10ALOX15CYP1A2CYP2D6 | |
| SCHEMBL28943606 | 0.85 | LMNA (0.33) | LMNAHSD17B10ALOX15CYP1A2CYP2D6 | |
| SCHEMBL25379497 | 0.84 | LMNA (0.32) | LMNAHSD17B10ALOX15CYP1A2CYP2D6 | |
| SCHEMBL28960243 | 0.77 | ALOX15 (0.33) | LMNAHSD17B10ALOX15CYP1A2CYP2D6 | |
| SCHEMBL4450655 | 0.76 | — | — | |
| SCHEMBL9685316 | 0.75 | — | — | |
| SCHEMBL5452684 | 0.75 | LMNA (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL12216619 | 0.73 | — | — | |
| SCHEMBL18341172 | 0.73 | LMNA (0.31) | LMNAHSD17B10ALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL18625595 | 0.73 | LMNA (0.31) | LMNAHSD17B10ALOX15CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111201021-B | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118496221-A | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-16 | — | — | CN | disclosed |