Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862631 | 0.78 | NAAA (0.53) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1852984 | 0.76 | MLYCD (0.51) | NAAASMN1; SMN2L3MBTL1MLYCDFOLH1 | |
| SCHEMBL1862628 | 0.75 | NAAA (0.49) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1853396 | 0.74 | MLYCD (0.47) | NAAAL3MBTL1MLYCD | |
| SCHEMBL5039845 | 0.74 | NAAA (0.56) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL421014 | 0.74 | NAAA (1.00) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8204741 | 0.74 | NAAA (1.00) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1004555 | 0.74 | NAAA (1.00) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1002638 | 0.74 | NAAA (1.00) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1002305 | 0.74 | NAAA (1.00) | NAAANPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |