Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828 | 0.87 | CA2 (0.54) | CA2PDPK1MCL1NPC1RAB9A | |
| SCHEMBL22459325 | 0.86 | CA2 (0.50) | CA2KIF11CYP11B1CYP11B2RARB | |
| SCHEMBL1487566 | 0.77 | CA2 (0.42) | CA2PDPK1MCL1NPC1RAB9A | |
| SCHEMBL79271 | 0.76 | CA2 (0.57) | CA2 | |
| SCHEMBL5826 | 0.76 | PDPK1 (0.48) | CA2PDPK1NPC1RAB9AMTNR1B | |
| SCHEMBL8164059 | 0.75 | HSD17B1 (0.41) | CA2KIF11FFAR4CYP11B1CYP11B2 | |
| SCHEMBL1874305 | 0.75 | RARB (0.44) | CA2KIF11CYP11B1CYP11B2RARB | |
| SCHEMBL7027476 | 0.74 | CYP2C9 (0.44) | CA2FFAR4ALDH1A1MAPK1 | |
| SCHEMBL23652736 | 0.73 | CA2 (0.54) | CA2KIF11FFAR4ALDH1A1MAPK1 | |
| SCHEMBL2269724 | 0.71 | KIF11 (0.47) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494003-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011050893-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | WO | disclosed |