Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826 | 0.88 | PDPK1 (0.48) | CA2PDPK1PYCR1MTNR1BNPC1 | |
| SCHEMBL1862883 | 0.87 | CA2 (0.50) | CA2PDPK1MTNR1BNPC1RAB9A | |
| SCHEMBL1487566 | 0.85 | CA2 (0.42) | CA2PDPK1NPC1DGAT1USP28 | |
| SCHEMBL1310562 | 0.81 | PDPK1 (0.42) | CA2PDPK1PYCR1MTNR1BNPC1 | |
| SCHEMBL6691430 | 0.81 | TYR (0.47) | PDPK1PYCR1MTNR1BNPC1KDM1A | |
| SCHEMBL2818682 | 0.80 | PDPK1 (0.56) | PDPK1MTNR1BNPC1DGAT1AKR1B1 | |
| SCHEMBL79271 | 0.80 | CA2 (0.57) | CA2 | |
| SCHEMBL20465747 | 0.79 | PYCR1 (0.46) | PDPK1PYCR1NPC1DGAT1USP28 | |
| SCHEMBL507839 | 0.79 | PYCR1 (0.46) | PDPK1PYCR1NPC1DGAT1USP28 | |
| SCHEMBL223670 | 0.79 | TYR (0.47) | PDPK1PYCR1MTNR1BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115926807-A | Liquid crystal medium and application | 深圳市和力信材料有限公司 | 2023-04-07 | — | — | CN | disclosed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | disclosed |
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | disclosed |
| EP-2344494-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | Signal Pharmaceuticals, LLC (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | disclosed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |