Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26296615 | 0.82 | FKBP1A (0.49) | CYP3A4FKBP1AALDH1A1KLK5TSHR | |
| SCHEMBL17643432 | 0.82 | CYP2C19 (0.44) | CYP3A4CYP2C9CYP2C19FKBP1AALDH1A1 | |
| SCHEMBL16277574 | 0.78 | MMP2 (0.46) | MMP2ANPEPCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL16282515 | 0.78 | MMP2 (0.46) | MMP2ANPEPCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL26310890 | 0.78 | NPSR1 (0.49) | FKBP1AALDH1A1TSHRMAPTNPSR1 | |
| SCHEMBL2126991 | 0.78 | NPSR1 (0.49) | FKBP1AALDH1A1TSHRMAPTNPSR1 | |
| SCHEMBL31561934 | 0.77 | FKBP1A (0.49) | MMP2ANPEPFKBP1AALDH1A1MAPT | |
| SCHEMBL26502806 | 0.76 | FKBP1A (0.43) | MMP2ANPEPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17009205 | 0.75 | LTA4H (0.47) | MMP2ANPEPFKBP1AALDH1A1LTA4H | |
| SCHEMBL27546320 | 0.72 | MMP2 (0.50) | MMP2ANPEPCYP2C19FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |