Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063617 | 0.85 | MAOA (0.47) | MAOAMAOBNOTUMALDH1A1POLB | |
| SCHEMBL15257805 | 0.84 | MAOA (0.43) | MAOAMAOBNOTUMALDH1A1POLB | |
| SCHEMBL8211039 | 0.82 | ALDH1A1 (0.48) | SMYD3ALDH1A1POLBKMT2AITGAV | |
| SCHEMBL21232781 | 0.80 | ITGAV (0.40) | MAOAMAOBNOTUMALDH1A1POLB | |
| SCHEMBL15121329 | 0.77 | SRC (0.47) | MAOAMAOBALDH1A1 | |
| SCHEMBL25014093 | 0.76 | ALDH1A1 (0.42) | MAOAMAOBALDH1A1KMT2ACA12 | |
| SCHEMBL26066647 | 0.76 | FOLH1 (0.42) | MAOAMAOBALDH1A1POLBKMT2A | |
| SCHEMBL12984349 | 0.76 | SMYD3 (0.44) | SMYD3ALDH1A1OPRM1OPRL1 | |
| SCHEMBL26066648 | 0.75 | FOLH1 (0.41) | MAOAMAOBALDH1A1POLBKMT2A | |
| SCHEMBL24346258 | 0.74 | SMYD3 (0.43) | SMYD3ALDH1A1OPRM1OPRL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399996-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170073360-A1 | BETA-LACTAMASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399996-B2 | Beta-lactamase inhibitors | MGAM, GAA, LCT | MAOA 206/4885MAOB 228/4885SMYD3 926/4885 |
| US-20170073360-A1 | BETA-LACTAMASE INHIBITORS | MGAM, GAA, LCT | MAOA 206/4885MAOB 228/4885SMYD3 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.