Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754653 | 0.90 | MAPT (0.41) | MAPTALDH1A1POLBPDE3BPDE3A | |
| SCHEMBL2486832 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1POLBLMNATSHR | |
| SCHEMBL756448 | 0.79 | LIPG (0.42) | MAPTALDH1A1POLBLMNAHTT | |
| SCHEMBL755131 | 0.78 | ALDH1A1 (0.39) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL752110 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL754217 | 0.75 | LIPG (0.40) | ALDH1A1POLBLMNATSHR | |
| SCHEMBL755241 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBLMNATSHR | |
| SCHEMBL752899 | 0.74 | LIPG (0.51) | ALDH1A1POLBLMNATSHR | |
| SCHEMBL758461 | 0.73 | ALDH1A1 (0.38) | ALDH1A1POLBLMNATSHR | |
| SCHEMBL2489852 | 0.73 | LIPG (0.44) | MAPTALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |