Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754217 | 0.91 | LIPG (0.40) | ALDH1A1POLBLIPGLMNATSHR | |
| SCHEMBL2489852 | 0.89 | LIPG (0.44) | ALDH1A1POLBLIPGMAPT | |
| SCHEMBL754653 | 0.89 | MAPT (0.41) | ALDH1A1POLBLIPGMAPTLMNA | |
| SCHEMBL755241 | 0.88 | ALDH1A1 (0.38) | ALDH1A1POLBLIPGLMNATSHR | |
| SCHEMBL754447 | 0.88 | LIPG (0.41) | ALDH1A1POLBLIPGMAPTLMNA | |
| SCHEMBL758461 | 0.87 | ALDH1A1 (0.38) | ALDH1A1POLBLIPGLMNATSHR | |
| SCHEMBL752862 | 0.86 | LIPG (0.41) | ALDH1A1POLBLIPGLMNATSHR | |
| SCHEMBL752899 | 0.86 | LIPG (0.51) | ALDH1A1POLBLIPGLMNATSHR | |
| SCHEMBL754682 | 0.86 | ALDH1A1 (0.39) | ALDH1A1POLBLIPGMAPTLMNA | |
| SCHEMBL753279 | 0.86 | ALDH1A1 (0.46) | ALDH1A1POLBLIPGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066754-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20150202208-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| EP-2181985-B1 | Antiviral Agent | SHIONOGI & CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20040229909-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229909-A1 | Antiviral agent | ZC3HAV1, ZC3HAV1L, DUT | ALDH1A1 658/4885POLB 89/4885LIPG 3541/4885 |
| US-20150202208-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | ALDH1A1 424/4885POLB 107/4885LIPG 4229/4885 |
| US-20170066754-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | ALDH1A1 424/4885POLB 107/4885LIPG 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.