SCHEMBL754653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18633409	0.90	MAPT (0.41)	MAPTALDH1A1POLBMEN1KMT2A
	SCHEMBL2486832	0.89	ALDH1A1 (0.41)	MAPTALDH1A1POLBLIPGLMNA
	SCHEMBL755131	0.88	ALDH1A1 (0.39)	MAPTALDH1A1POLBMEN1KMT2A
	SCHEMBL752110	0.87	ALDH1A1 (0.39)	MAPTALDH1A1POLBMEN1KMT2A
	SCHEMBL756448	0.87	LIPG (0.42)	MAPTALDH1A1POLBLIPGRXFP1
	SCHEMBL754217	0.83	LIPG (0.40)	ALDH1A1POLBLIPGRXFP1LMNA
	SCHEMBL2489852	0.81	LIPG (0.44)	MAPTALDH1A1POLBLIPG
	SCHEMBL755241	0.80	ALDH1A1 (0.38)	ALDH1A1POLBLIPGRXFP1LMNA
	SCHEMBL752899	0.80	LIPG (0.51)	ALDH1A1POLBLIPGLMNATSHR
	SCHEMBL754447	0.79	LIPG (0.41)	MAPTALDH1A1POLBLIPGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.