Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.52 |
| ▸ | ABHD6 | Q9BV23 | 11/20 | 0.48 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744467 | 0.85 | MGLL (0.54) | MGLLABHD6NPY2RPLA2G7FAAH | |
| SCHEMBL16744456 | 0.84 | MGLL (0.69) | MGLLABHD6NPY2R | |
| SCHEMBL15100759 | 0.81 | MGLL (0.52) | MGLLABHD6PLA2G7 | |
| SCHEMBL15100612 | 0.81 | MGLL (0.76) | MGLLABHD6PLA2G7FAAH | |
| SCHEMBL18500769 | 0.80 | GPR119 (0.57) | NPY2R | |
| SCHEMBL16744463 | 0.75 | MGLL (0.56) | MGLLABHD6PLA2G7 | |
| SCHEMBL16747546 | 0.74 | MGLL (0.66) | MGLLABHD6PLA2G7FAAH | |
| SCHEMBL14834316 | 0.74 | CYP2C9 (0.56) | MGLLFAAH | |
| SCHEMBL14834095 | 0.74 | MEN1 (0.59) | MGLLABHD6 | |
| SCHEMBL20198108 | 0.73 | MGLL (0.44) | MGLLABHD6NPY2RPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2023-10-05 | — | — | US | disclosed |
| US-11021453-B2 | Carbamate compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200270223-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2020-08-27 | — | — | US | disclosed |
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2018-07-26 | — | — | US | disclosed |
| US-9957242-B2 | Carbamate compounds and methods of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170073320-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021453-B2 | Carbamate compounds and methods of making and using same | ABHD6, ABHD16A, RABL6 | MGLL 60/4885ABHD6 1/4885NPY2R 4654/4885 |
| US-20200270223-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | MGLL 14/4885ABHD6 1/4885NPY2R 4640/4885 |
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | MGLL 14/4885ABHD6 1/4885NPY2R 4640/4885 |
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | MGLL 54/4885ABHD6 1/4885NPY2R 4661/4885 |
| US-20170073320-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | MGLL 14/4885ABHD6 1/4885NPY2R 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.