SCHEMBL20198108

SCHEMBL20198108

C=C/C=C(\C=C/C)C(O)(c1ccccc1)C1CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.44
ABHD6 Q9BV23 9/20 0.39
PLA2G7 Q13093 5/20 0.39
NPY2R P49146 2/20 0.39
CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26079420 0.78 MGLL (0.45) MGLLABHD6PLA2G7
SCHEMBL16744456 0.76 MGLL (0.69) MGLLABHD6NPY2R
SCHEMBL16744467 0.75 MGLL (0.54) MGLLABHD6PLA2G7NPY2R
SCHEMBL18634263 0.73 MGLL (0.52) MGLLABHD6PLA2G7NPY2R
SCHEMBL20198149 0.73 MGLL (0.48) MGLLABHD6PLA2G7
SCHEMBL26079437 0.72 MGLL (0.39) MGLLABHD6PLA2G7
SCHEMBL16744463 0.66 MGLL (0.56) MGLLABHD6PLA2G7
SCHEMBL14834316 0.65 CYP2C9 (0.56) MGLL
SCHEMBL14834227 0.65 MGLL (0.54) MGLLABHD6PLA2G7
SCHEMBL14834288 0.64 DRD2 (0.52) MGLLABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3326627-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2018-05-30 EP disclosed