Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630160 | 0.85 | THRA (0.46) | TGM2BACE1ERCC1ERCC4LMNA | |
| SCHEMBL18630143 | 0.84 | TGM2 (0.46) | TGM2LMNAMAPK1NLRP1GAA | |
| SCHEMBL28973935 | 0.82 | PKM (0.55) | TGM2HSD17B1LMNAALDH1A1KMT2A | |
| SCHEMBL18636751 | 0.82 | TGM2 (0.44) | TGM2LMNAMAPK1GAAMEN1 | |
| SCHEMBL18630144 | 0.81 | ALDH1A1 (0.49) | TRPA1BACE1ERCC1ERCC4HSD17B1 | |
| SCHEMBL29157949 | 0.81 | EGFR (0.49) | TGM2ALDH1A1MAPTEGFR | |
| SCHEMBL18630146 | 0.79 | TGM2 (0.42) | TGM2LMNAMAPK1NLRP1GAA | |
| SCHEMBL28987060 | 0.79 | TGM2 (0.49) | TGM2ERCC1ERCC4MAPK1GAA | |
| SCHEMBL8983177 | 0.79 | MEN1 (0.49) | TGM2ERCC1ERCC4LMNAALDH1A1 | |
| SCHEMBL11795978 | 0.78 | TGM2 (0.50) | TGM2ERCC1ERCC4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518863-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-11-15 | — | — | EP | disclosed |
| EP-3653194-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | Dentsply DeTrey GmbH (DE) | 2020-05-20 | — | — | EP | disclosed |
| EP-3536303-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2019-09-11 | — | — | EP | disclosed |
| EP-3141567-B1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GMBH (DE) | 2019-08-28 | — | — | EP | disclosed |
| WO-2018060516-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2017042333-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GMBH (DE) | 2017-03-16 | — | — | WO | disclosed |
| EP-3141567-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GmbH (DE) | 2017-03-15 | — | — | EP | disclosed |