Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143351 | 0.75 | NPC1 (0.46) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20197335 | 0.75 | RAB9A (0.38) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9246865 | 0.73 | CHRM2 (0.44) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19882438 | 0.73 | CHRM2 (0.41) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1196329 | 0.72 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL26046875 | 0.72 | KMT2A (0.33) | SMN1; SMN2KMT2AGAA | |
| SCHEMBL14068359 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL24103475 | 0.71 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10193856 | 0.71 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30448897 | 0.71 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764053-B1 | IRON(II) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING (US) | 2017-03-15 | — | — | EP | disclosed |