Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882438 | 0.80 | CHRM2 (0.41) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7961155 | 0.76 | CHRM2 (0.42) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18639384 | 0.73 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL25211342 | 0.73 | CHRM2 (0.68) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14067286 | 0.71 | CHRM2 (0.61) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4550158 | 0.71 | CHRM2 (0.43) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3395752 | 0.71 | SMN1; SMN2 (0.59) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11569803 | 0.71 | CHRM2 (0.53) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL230222 | 0.71 | CHRM2 (0.70) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29438821 | 0.71 | CHRM2 (0.70) | CHRM2KDM4ESMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482985-B1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-20120135959-A1 | Metalloprotein inhibitors containing nitrogen based ligands | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2012-05-31 | — | — | US | disclosed |
| US-20120135959-A1 | Metalloprotein inhibitors containing nitrogen based ligands | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135959-A1 | Metalloprotein inhibitors containing nitrogen based ligands | MMP8, MMP1, TIMP3 | CHRM2 3690/4885KDM4E 2887/4885SMN1; SMN2 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.