SCHEMBL1864087

SCHEMBL1864087

CN(N)c1ccc([N+](=O)[O-])c2occc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 6/20 0.34
POLB P06746 2/20 0.34
PKM P14618 1/20 0.34
HCAR3 P49019 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 2/20 0.33
PAX8 Q06710 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 2/20 0.32
CYP3A4 P08684 1/20 0.32
VCAM1 P19320 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
NSD2 O96028 1/20 0.31
NCOA1 Q15788 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28357320 0.88 ALDH1A1 (0.45) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL1055128 0.72 TDP1 (0.48) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL27865031 0.72 LMNA (0.41) LMNAALDH1A1KDM4EHTTMAPT
SCHEMBL29390318 0.72 TDP1 (0.48) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL8159648 0.72 VCAM1 (0.43) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL27899102 0.72 LMNA (0.38) LMNAMEN1KMT2AHTTMAPT
SCHEMBL1484117 0.71 MEN1 (0.66) MEN1KMT2AHTTMAPTPOLB
SCHEMBL2260017 0.69 SMN1; SMN2 (0.45) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL4992504 0.68 SIRT6 (0.45) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL27953903 0.68 LMNA (0.47) LMNAMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090220381-A1 IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME NESTEC S.A. (CH) 2009-09-03 US claimed
WO-2007059265-A2 IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME WORCESTER POLYTECHNIC INSTITUTE (US) 2007-05-24 WO claimed
US-20070042450-A1 Multi-transduction mechanism based microfluidic analyte sensors WORCESTER POLYTECHNIC INSTITUTE (US) 2007-02-22 US claimed
WO-2006113440-A2 MULTI-TRANSDUCTION MECHANISM BASED MICROFLUIDIC ANALYTE SENSORS WORCESTER POLYTECHNIC INSTITUTE (US) 2006-10-26 WO claimed
US-7935309-B2 Multi-transduction mechanism based microfluidic analyte sensors WORCESTER POLYTECHNIC INSTITUTE (US) 2011-05-03 US disclosed
US-20090220381-A1 IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME NESTEC S.A. (CH) 2009-09-03 US disclosed
WO-2007059265-A2 IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME WORCESTER POLYTECHNIC INSTITUTE (US) 2007-05-24 WO disclosed
US-20070042450-A1 Multi-transduction mechanism based microfluidic analyte sensors WORCESTER POLYTECHNIC INSTITUTE (US) 2007-02-22 US disclosed
WO-2006113440-A2 MULTI-TRANSDUCTION MECHANISM BASED MICROFLUIDIC ANALYTE SENSORS WORCESTER POLYTECHNIC INSTITUTE (US) 2006-10-26 WO disclosed