Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643176 | 0.87 | ALDH1A1 (0.41) | SNCALMNACNR1KMT2A | |
| SCHEMBL18643353 | 0.77 | FAAH (0.49) | FAAHLMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL892448 | 0.73 | SNCA (0.75) | SNCA | |
| SCHEMBL18643118 | 0.70 | GCGR (0.42) | SNCAFAAHLMNAMAPTSMN1; SMN2 | |
| SCHEMBL15932176 | 0.67 | GLS (0.48) | FAAH | |
| SCHEMBL892345 | 0.65 | SNCA (0.74) | SNCA | |
| SCHEMBL15932078 | 0.65 | SRD5A2 (0.50) | FAAHLMNASMN1; SMN2 | |
| SCHEMBL892098 | 0.64 | SNCA (0.73) | SNCA | |
| SCHEMBL20524122 | 0.63 | HDAC6 (0.73) | FAAHLMNAMAPTSMN1; SMN2 | |
| SCHEMBL891788 | 0.62 | SNCA (0.74) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440550-B1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV LEUVEN KATH (BE) | 2017-03-15 | — | — | EP | disclosed |