Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076558 | 1.00 | CALCRL (0.40) | CALCRLCYP3A4OPRM1OPRK1OPRL1 | |
| SCHEMBL28233724 | 0.94 | BTK (0.37) | CALCRLOPRM1OPRK1OPRL1DRD2 | |
| SCHEMBL18644664 | 0.88 | JAK2 (0.49) | PARP1PARP2ACHE | |
| SCHEMBL16143648 | 0.86 | PIK3CD (0.38) | CALCRLOPRM1OPRK1OPRL1BCHE | |
| SCHEMBL20480742 | 0.86 | PIK3CD (0.38) | CALCRLOPRM1OPRK1OPRL1BCHE | |
| SCHEMBL18285521 | 0.85 | OPRM1 (0.40) | CALCRLOPRM1DRD2DRD4DRD3 | |
| SCHEMBL18285527 | 0.85 | OPRM1 (0.40) | CALCRLOPRM1DRD2DRD4DRD3 | |
| SCHEMBL18645213 | 0.83 | HTR6 (0.47) | PARP1PARP2BCHEACHE | |
| SCHEMBL15155889 | 0.81 | EGFR (0.39) | — | |
| SCHEMBL25616566 | 0.81 | CHRM1 (0.44) | OPRM1OPRK1OPRL1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-B | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105753863-A | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2016-07-13 | — | — | CN | disclosed |