Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366547 | 0.85 | HSP90AA1 (0.49) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL17500060 | 0.82 | ESR2 (0.47) | ALOX5PTGS1PTGS2CYP1A2CYP2C9 | |
| SCHEMBL19732817 | 0.79 | GABRA1 (0.50) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28121289 | 0.77 | ALDH1A1 (0.52) | ALOX5MEN1KMT2AAKR1C2AKR1C1 | |
| SCHEMBL31720848 | 0.77 | POLB (0.42) | MEN1KMT2APOLBCNR1 | |
| SCHEMBL15674488 | 0.76 | NPSR1 (0.40) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL17500122 | 0.76 | HDAC4 (0.47) | ALOX5MEN1KMT2AESR1ESR2 | |
| SCHEMBL3672236 | 0.75 | CA2 (0.55) | ALOX5PTGS1PTGS2CYP1A2CYP2C9 | |
| SCHEMBL18645759 | 0.72 | KIF11 (0.54) | ALOX5PTGS1PTGS2CYP1A2CYP2C9 | |
| SCHEMBL201609 | 0.72 | GABRA1 (0.57) | CYP1A2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044889-A1 | LRH-1 MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-16 | — | — | WO | disclosed |