Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911539 | 0.85 | SLC6A4 (0.49) | PPARGPPARASLC6A4KMOKCNH2 | |
| SCHEMBL14662201 | 0.84 | SOS1 (0.60) | LTA4HTSHRSLC6A4KMOKCNH2 | |
| SCHEMBL21835261 | 0.82 | MAOA (0.55) | TSHRSLC6A4KCNH2HTR2AALDH1A1 | |
| SCHEMBL15385004 | 0.82 | SLC6A4 (0.47) | SLC6A4KCNH2HTR2AALDH1A1MAPT | |
| SCHEMBL5537459 | 0.82 | KMO (0.41) | PPARGPPARASLC6A4KMOKCNH2 | |
| SCHEMBL10614755 | 0.81 | KMO (0.62) | LTA4HTSHRSLC6A4KMOKCNH2 | |
| SCHEMBL4336604 | 0.81 | SOS1 (0.56) | LTA4HTSHRSLC6A4HTR2AALDH1A1 | |
| SCHEMBL14753507 | 0.80 | LTA4H (0.48) | LTA4HTSHRALDH1A1MAPTKMT2A | |
| Dimethylamine SCHEMBL27666829 | 0.79 | SLC6A4 (0.58) | SLC6A4KCNH2HTR2AALDH1A1MAPT | |
| SCHEMBL14661923 | 0.78 | POLB (0.50) | PPARGPPARASLC6A4KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247808-A1 | Heterocyclic Tec-Family Kinase Inhibitors | GB005, INC. | 2020-08-06 | — | — | US | disclosed |
| WO-2017041180-A1 | HETEROCYCLIC TEC-FAMILY KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247808-A1 | Heterocyclic Tec-Family Kinase Inhibitors | TEC, BTK, LCK | PPARG 4663/4885PPARA 4756/4885LTA4H 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.