Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770690 | 0.82 | CYP19A1 (0.41) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL15782891 | 0.82 | HTR2A (0.51) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL14594165 | 0.81 | ACACB (0.47) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL16479302 | 0.81 | HTR7 (0.46) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL18856958 | 0.78 | HTR7 (0.44) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL18856945 | 0.78 | PLG (0.45) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL16216132 | 0.78 | HTR7 (0.44) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL12257510 | 0.77 | RORC (0.45) | HTR7PLGPLAUMTNR1AMTNR1B | |
| SCHEMBL23612457 | 0.77 | KMO (0.54) | HTR7MTNR1AMTNR1BTP53RORC | |
| SCHEMBL2035199 | 0.76 | CDK4 (0.63) | MTNR1AMTNR1BCDK4CCND1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597310-B2 | Indanyloxydihydrobenzofuranylacetic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-21 | — | — | US | disclosed |