Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.67 |
| ▸ | MMP9 | P14780 | 7/20 | 0.67 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 4/20 | 0.59 |
| ▸ | MMP3 | P08254 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP7 | P09237 | 2/20 | 0.59 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284050 | 0.90 | ALDH1A1 (0.71) | MMP2MMP9ADAMTS4ALDH1A1CYP1A2 | |
| SCHEMBL11456951 | 0.88 | ALDH1A1 (0.74) | MMP2MMP9ADAMTS4NR3C1ALDH1A1 | |
| SCHEMBL18649870 | 0.85 | ADAMTS4 (0.68) | MMP2MMP9ADAMTS4NR3C1MMP13 | |
| SCHEMBL13889012 | 0.85 | ALDH1A1 (0.83) | MMP2MMP9ADAMTS4NR3C1MMP13 | |
| SCHEMBL20021999 | 0.84 | MMP2 (0.63) | MMP2MMP9ADAMTS4NR3C1MMP13 | |
| SCHEMBL6326378 | 0.83 | ADAMTS4 (0.65) | MMP2MMP9ADAMTS4NR3C1MMP13 | |
| SCHEMBL6326385 | 0.83 | ADAMTS4 (0.65) | MMP2MMP9ADAMTS4NR3C1MMP13 | |
| SCHEMBL5706203 | 0.82 | ALDH1A1 (0.57) | MMP2MMP9ADAMTS4MMP13MMP7 | |
| SCHEMBL18649638 | 0.81 | MMP2 (0.75) | MMP2MMP9ADAMTS4MMP13MMP3 | |
| SCHEMBL16380450 | 0.81 | MMP2 (0.79) | MMP2MMP9ADAMTS4MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598383-B2 | Reactive oxygen species-based prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |