Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 6/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873326 | 0.81 | EDNRA (0.53) | EDNRACKS1BSKP2PTGS2 | |
| SCHEMBL1872226 | 0.75 | CKS1B (0.47) | CYP11B1CYP11B2ALPLCKS1BSKP2 | |
| SCHEMBL16445741 | 0.65 | CYP11B1 (0.51) | PDK2CYP11B1CYP11B2SCN9AKDR | |
| SCHEMBL28404373 | 0.64 | PTGS2 (0.54) | CYP11B1EDNRAPTGS2 | |
| SCHEMBL3717538 | 0.62 | CA12 (0.43) | EDNRAPTGS2 | |
| SCHEMBL11291071 | 0.62 | PTGS2 (0.55) | CYP11B1EDNRAPTGS2 | |
| SCHEMBL30863682 | 0.62 | PTGS2 (0.55) | CYP11B1EDNRAPTGS2 | |
| SCHEMBL5488230 | 0.61 | CA2 (0.56) | CYP11B1EDNRAPTGS2 | |
| SCHEMBL28462214 | 0.61 | STAT3 (0.52) | PTGS2 | |
| SCHEMBL13362351 | 0.60 | NPY5R (0.67) | CYP11B1CYP11B2ABL1OPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |