Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873326 | 0.80 | EDNRA (0.53) | CKS1BSKP2PTGS2KMT2ANAMPT | |
| SCHEMBL1865060 | 0.75 | PDK2 (0.38) | CKS1BSKP2PTGS2ALPLCYP11B1 | |
| SCHEMBL5990332 | 0.71 | CYP11B1 (0.51) | PTGS1PTGS2CYP11B1CYP11B2KDR | |
| SCHEMBL15009839 | 0.70 | CYP11B1 (0.50) | PTGS1PTGS2CYP11B1CYP11B2KDR | |
| SCHEMBL20458034 | 0.70 | CKS1B (0.60) | CKS1BSKP2TSHRKMT2AIDH2 | |
| SCHEMBL30545136 | 0.70 | CNR1 (0.56) | CYP11B1CYP11B2KDRDGAT1KCNH2 | |
| SCHEMBL14832292 | 0.70 | CNR1 (0.56) | CYP11B1CYP11B2KDRDGAT1KCNH2 | |
| SCHEMBL31661850 | 0.69 | MKNK1 (0.55) | CYP11B1CYP11B2KDREGFRFGFR1 | |
| Hydrochloric Acid SCHEMBL27927303 | 0.68 | MKNK1 (0.53) | CYP11B1CYP11B2KDREGFRFGFR1 | |
| SCHEMBL15989428 | 0.67 | CYP11B1 (0.53) | CYP11B1CYP11B2KDREGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | claimed |
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |