Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.53 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 3/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872226 | 0.80 | CKS1B (0.47) | PTGS2NAMPTCKS1BSKP2KMT2A | |
| SCHEMBL28404373 | 0.79 | PTGS2 (0.54) | EDNRAEDNRBPTGS2NAMPTALDH1A1 | |
| SCHEMBL11291071 | 0.77 | PTGS2 (0.55) | EDNRAEDNRBPTGS2NAMPTALDH1A1 | |
| SCHEMBL30863682 | 0.77 | PTGS2 (0.55) | EDNRAEDNRBPTGS2NAMPTALDH1A1 | |
| SCHEMBL5488230 | 0.75 | CA2 (0.56) | EDNRAEDNRBPTGS2NAMPTALDH1A1 | |
| SCHEMBL18921577 | 0.75 | PTGS2 (0.60) | EDNRAEDNRBPTGS2NAMPTCYP3A4 | |
| SCHEMBL20541087 | 0.70 | CYP2A6 (0.70) | PTGS2ALDH1A1TP53CYP2A6CYP1A2 | |
| SCHEMBL30026143 | 0.70 | CYP2A6 (0.70) | PTGS2ALDH1A1TP53CYP2A6CYP1A2 | |
| SCHEMBL8350252 | 0.70 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL15920333 | 0.68 | CYP2A6 (0.50) | PTGS2ALDH1A1TP53CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496577-A1 | IMIDAZOPYRIDINE DERIVATIVES | Piramal Life Sciences Limited (IN) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011055320-A1 | IMIDAZOPYRIDINE DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |