Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257812 | 0.89 | TDP1 (0.52) | TDP1PRKCAALDH1A1ARCHRM1 | |
| SCHEMBL16684801 | 0.88 | ALDH1A1 (0.47) | TDP1ALOX15PRKCAALDH1A1AR | |
| SCHEMBL13825187 | 0.87 | ALOX15 (0.44) | TDP1ALOX15PRKCAALDH1A1CHRM5 | |
| SCHEMBL21268589 | 0.86 | TDP1 (0.43) | TDP1PRKCAALDH1A1ARTSHR | |
| Triacetin SCHEMBL821340 | 0.84 | TDP1 (0.56) | TDP1PRKCAALDH1A1ARTSHR | |
| Triacetin SCHEMBL3870 | 0.84 | TDP1 (0.56) | TDP1PRKCAALDH1A1ARTSHR | |
| SCHEMBL8362220 | 0.83 | PRKCA (0.47) | TDP1PRKCAALDH1A1ARTSHR | |
| SCHEMBL7758842 | 0.83 | PRKCA (0.47) | TDP1PRKCAALDH1A1ARTSHR | |
| SCHEMBL11913587 | 0.83 | ALDH1A1 (0.45) | TDP1ALOX15PRKCAALDH1A1CHRM5 | |
| SCHEMBL7757645 | 0.83 | PRKCA (0.44) | TDP1ALOX15PRKCAALDH1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046535-A1 | MULTI-FUNCTIONALIZED POLYSACCHARIDE COMPOUNDS AND USE THEREOF FOR TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | NANOMEDSYN (FR) | 2017-03-23 | — | — | WO | disclosed |