Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653128 | 0.82 | SMN1; SMN2 (0.34) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653152 | 0.81 | GAA (0.33) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653130 | 0.79 | RIPK1 (0.35) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653070 | 0.76 | SMN1; SMN2 (0.36) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653233 | 0.75 | MAPT (0.35) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653224 | 0.74 | SMN1; SMN2 (0.35) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653134 | 0.69 | LMNA (0.41) | GAAHPGD | |
| SCHEMBL20707118 | 0.67 | SMN1; SMN2 (0.39) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL18653160 | 0.67 | GLA (0.34) | GAA | |
| SCHEMBL18653174 | 0.66 | IDO1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |