Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653070 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGAANPY1RNPY2R | |
| SCHEMBL18653128 | 0.77 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDGAANPY1RNPY2R | |
| SCHEMBL18653224 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDGAALMNAALDH1A1 | |
| SCHEMBL18653145 | 0.75 | GAA (0.30) | SMN1; SMN2HPGDGAA | |
| SCHEMBL20707119 | 0.74 | CCR8 (0.32) | SMN1; SMN2HPGDGAAMEN1KMT2A | |
| SCHEMBL24592686 | 0.74 | ESR1 (0.46) | HPGDGAAALDH1A1ESR1 | |
| SCHEMBL18653238 | 0.71 | LMNA (0.35) | HPGDGAALMNAALDH1A1MAPT | |
| SCHEMBL6678858 | 0.70 | OPRM1 (0.44) | ADRB2 | |
| SCHEMBL19445752 | 0.69 | GPR84 (0.35) | ALDH1A1ADRB2 | |
| SCHEMBL18653233 | 0.69 | MAPT (0.35) | SMN1; SMN2HPGDGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438106-A1 | ANTI-VIRAL COMPOUNDS | AbbVie Ireland Unlimited Company (IE) | 2019-02-06 | — | — | EP | disclosed |