Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653134 | 0.94 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL23891777 | 0.82 | AKR1C3 (0.41) | LMNAALDH1A1HTTTP53 | |
| SCHEMBL8750377 | 0.82 | LMNA (0.34) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL18653238 | 0.80 | LMNA (0.35) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL11057467 | 0.78 | ALDH1A1 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL29503546 | 0.78 | ALDH1A1 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL25852510 | 0.78 | HTR2A (0.38) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL20939899 | 0.77 | TAAR1 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL17086648 | 0.77 | ABCB11 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL23891676 | 0.74 | TRPA1 (0.34) | LMNATRPA1PTGS1CACNA1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |