Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 13/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.31 |
| ▸ | CDK9 | P50750 | 5/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968370 | 0.79 | SMPD3 (0.52) | SMPD3 | |
| SCHEMBL30716383 | 0.76 | FLT3 (0.39) | FLT3PIK3CACCNT1CDK9CDK7 | |
| SCHEMBL22103759 | 0.73 | CDK2 (0.40) | CCNT1CDK9CDK7 | |
| SCHEMBL402500 | 0.70 | TGFBR1 (0.50) | — | |
| SCHEMBL20903438 | 0.70 | FLT3 (0.38) | FLT3PIK3CACCNT1CDK9PDE2A | |
| SCHEMBL20356713 | 0.69 | PKM (0.42) | — | |
| SCHEMBL17830895 | 0.69 | SCN5A (0.47) | FLT3PIK3CACCNT1CDK9CDK7 | |
| SCHEMBL21238680 | 0.68 | CDK7 (0.33) | CCNT1CDK9CDK7 | |
| SCHEMBL19102376 | 0.68 | FLT3 (0.39) | FLT3PIK3CACCNT1CDK9CDK7 | |
| SCHEMBL16553434 | 0.67 | FLT3 (0.40) | FLT3PIK3CACCNT1CDK9SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233645-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | 浙江海正药业股份有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |
| EP-2768509-B1 | SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2017-03-22 | — | — | EP | disclosed |