Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 7/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650739 | 0.89 | L3MBTL1 (0.47) | MAOAKDM1AATMNCF1MAPT | |
| SCHEMBL18655358 | 0.85 | MAOA (0.43) | MAOAKDM1AMAPTL3MBTL1KDM4E | |
| SCHEMBL18655357 | 0.84 | MAOA (0.49) | MAOAKDM1AMAPTL3MBTL1KDM4E | |
| SCHEMBL18655360 | 0.83 | CCR1 (0.47) | KDM1AATMMAPTL3MBTL1KDM4E | |
| SCHEMBL18631798 | 0.82 | POLB (0.49) | MAOAMAPTKDM4ELMNAPOLB | |
| SCHEMBL5410460 | 0.81 | KDM1A (0.66) | MAOAKDM1AATMMAPTNUDT1 | |
| Iodide SCHEMBL17187186 | 0.79 | KDM1A (0.63) | MAOAKDM1AATMMAPTNUDT1 | |
| SCHEMBL18655362 | 0.78 | KMT2A (0.49) | MAOAMAPTKDM4EPOLBKMT2A | |
| SCHEMBL18655356 | 0.78 | LRRK2 (0.47) | KDM1AATMMAPTNUDT1KDM4E | |
| SCHEMBL18678491 | 0.77 | MAOA (0.73) | MAOAATMMAPTL3MBTL1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081351-A1 | Design, Synthesis, and Biological Activity of Platinum-benz[c]acridine Hybrid Agents and Methods Associated Therewith | WAKE FOREST UNIVERSITY | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081351-A1 | Design, Synthesis, and Biological Activity of Platinum-benz[c]acridine Hybrid Agents and Methods Associated Therewith | ACR, TP53, MCL1 | MAOA 2459/4885KDM1A 3582/4885ATM 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.