SCHEMBL18655382

SCHEMBL18655382

O=C1CCSc2ccc(CI)cc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.58
ELOC Q15369 1/20 0.58
ELOB Q15370 1/20 0.58
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 2/20 0.45
HTT P42858 3/20 0.43
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
CTSL P07711 1/20 0.36
CA2 P00918 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
RYR2 Q92736 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10891508 0.83 VHL (0.58) VHLELOCELOBALDH1A1KDM4E
SCHEMBL90878 0.78 VHL (0.53) VHLELOCELOBALDH1A1KDM4E
SCHEMBL69545 0.77 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL12743 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL10720643 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL6592045 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL69544 0.74 VHL (1.00) VHLELOCELOBALDH1A1KDM4E
SCHEMBL29595944 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL69249 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E
SCHEMBL56657 0.74 VHL (0.64) VHLELOCELOBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484526-B1 INKJET RECORDING METHOD AND PRINTED MATERIAL FUJIFILM CORP (JP) 2017-03-22 EP disclosed