Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 5/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20796625 | 0.81 | PSMB8 (0.40) | PRKDCPGRNR3C1ARKMT2A | |
| SCHEMBL18655469 | 0.78 | PRKDC (0.36) | PRKDCPGRNR3C1ARHPGD | |
| SCHEMBL20796392 | 0.76 | KDM4E (0.36) | PRKDCHPGDKMT2AMAOBMAOA | |
| SCHEMBL18659843 | 0.75 | CYP1A2 (0.38) | HPGDKMT2AL3MBTL1MAOBMAOA | |
| SCHEMBL28289176 | 0.70 | MAOB (0.56) | PRKDCPGRNR3C1ARHPGD | |
| SCHEMBL14437149 | 0.68 | ALDH1A1 (0.49) | ARHPGDKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14437131 | 0.66 | IGLV6-57 (0.46) | PGRNR3C1ARHPGDKMT2A | |
| SCHEMBL20314437 | 0.64 | MEN1 (0.55) | PRKDCHPGDKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12732259 | 0.64 | NR3C1 (0.34) | PGRNR3C1AR | |
| SCHEMBL11029649 | 0.63 | ALDH2 (0.49) | PGRHPGDKMT2AL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222390-B2 | Near-infrared fluorescent sensors for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |