Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928067 | 0.81 | LMNA (0.37) | MEN1NR2F2KMT2ASLC22A12LMNA | |
| SCHEMBL25526909 | 0.81 | SLC22A12 (0.36) | MEN1NR2F2KMT2ASELEVCAM1 | |
| SCHEMBL23885609 | 0.77 | RAB9A (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18640792 | 0.77 | HSD17B10 (0.32) | ALDH1A1LMNA | |
| SCHEMBL12410481 | 0.75 | SELE (0.35) | MEN1NR2F2KMT2ASELEVCAM1 | |
| SCHEMBL30893392 | 0.74 | NPC1 (0.35) | MEN1NR2F2KMT2ASELEVCAM1 | |
| SCHEMBL15218164 | 0.74 | NPC1 (0.35) | MEN1NR2F2KMT2ASELEVCAM1 | |
| SCHEMBL22509663 | 0.74 | SELE (0.34) | MEN1NR2F2KMT2ASELEVCAM1 | |
| SCHEMBL17406862 | 0.73 | SRC (0.40) | — | |
| SCHEMBL22857613 | 0.73 | HTT (0.38) | MEN1NR2F2KMT2AENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046738-A1 | TRIAZOLONE COMPOUNDS AS PERK INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-23 | — | — | WO | disclosed |