Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928067 | 0.88 | LMNA (0.37) | SLC22A12P2RX7MEN1KMT2ANR2F2 | |
| SCHEMBL23885609 | 0.83 | RAB9A (0.45) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL18656790 | 0.81 | MEN1 (0.36) | SLC22A12SELEVCAM1MEN1KMT2A | |
| SCHEMBL18547854 | 0.74 | SLC22A12 (0.39) | SLC22A12SELEVCAM1P2RX7MEN1 | |
| SCHEMBL27949493 | 0.72 | SLC22A12 (0.31) | SLC22A12MEN1KMT2ANR2F2 | |
| SCHEMBL13860102 | 0.71 | HRH3 (0.35) | ACACBNPC1 | |
| SCHEMBL12410481 | 0.71 | SELE (0.35) | SLC22A12SELEVCAM1MEN1KMT2A | |
| SCHEMBL23885208 | 0.71 | XDH (0.37) | ADORA2BALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL30893392 | 0.70 | NPC1 (0.35) | SELEVCAM1MEN1KMT2ANR2F2 | |
| SCHEMBL15218164 | 0.70 | NPC1 (0.35) | SELEVCAM1MEN1KMT2ANR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | SLC22A12 3155/4885SELE 1193/4885VCAM1 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.