Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628004 | 1.00 | GAA (0.49) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL18628003 | 1.00 | GAA (0.49) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL20386935 | 0.97 | GAA (0.50) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL18628002 | 0.97 | GAA (0.50) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL18628001 | 0.97 | GAA (0.50) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL23037147 | 0.86 | LMNA (0.53) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL23037148 | 0.86 | LMNA (0.53) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL20179294 | 0.86 | GAA (0.48) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL21581856 | 0.86 | GAA (0.48) | GAAHTTLMNAHPGDALDH1A1 | |
| SCHEMBL158896 | 0.86 | GAA (0.55) | GAAHTTLMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350150-B1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | EVONIK OPERATIONS GMBH (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-10233139-B2 | Alkenylphenoxy-substituted 1,1-diphenylethylenes, processes for their preparation, and their use | EVONIK TECHNOCHEMIE GMBH (DE) | 2019-03-19 | — | — | US | disclosed |
| US-20180201561-A1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-07-19 | — | — | US | disclosed |
| WO-2017045932-A1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| EP-3144290-A1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Evonik Technochemie GmbH (DE) | 2017-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201561-A1 | ALKENYLPHENOXY-SUBSTITUTED 1,1-DIPHENYLETHYLENES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | MACF1, COL1A1, PLOD1 | GAA 4566/4885HTT 2585/4885LMNA 572/4885 |
| US-10233139-B2 | Alkenylphenoxy-substituted 1,1-diphenylethylenes, processes for their preparation, and their use | MACF1, COL1A1, PLOD1 | GAA 4535/4885HTT 1894/4885LMNA 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.