Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742630 | 0.93 | MAPK14 (0.48) | MAPK14KDM4ENPC1CYP1A2TGFBR1 | |
| SCHEMBL18657149 | 0.90 | NPC1 (0.46) | KDM4ENPC1CYP1A2TGFBR1CYP2A6 | |
| SCHEMBL16882962 | 0.86 | GRM5 (0.43) | MAPK14KDM4ENPC1CYP1A2TGFBR1 | |
| SCHEMBL21742858 | 0.83 | NPC1 (0.42) | NPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21022955 | 0.83 | NPC1 (0.49) | MAPK14KDM4ENPC1CYP1A2TGFBR1 | |
| SCHEMBL9974919 | 0.83 | LMNA (0.50) | KDM4ENPC1CYP1A2TGFBR1CYP2D6 | |
| SCHEMBL4769511 | 0.83 | CHEK2 (0.46) | MAPK14KDM4ENPC1CYP1A2TGFBR1 | |
| SCHEMBL7930011 | 0.82 | L3MBTL1 (0.47) | KDM4ENPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18571558 | 0.82 | BTK (0.49) | KDM4ENPC1CYP1A2TGFBR1TP53 | |
| SCHEMBL18174588 | 0.82 | RET (0.41) | MAPK14KDM4ENPC1CYP2A6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | MAPK14 3076/4885KDM4E 3201/4885NPC1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.