Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146034 | 0.86 | IDO1 (0.45) | MAPTGAAL3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL18660184 | 0.84 | HTT (0.47) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL14831872 | 0.83 | HPGD (0.50) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL18232475 | 0.81 | LOXL2 (0.41) | CA1CA2CA12CA9 | |
| SCHEMBL25018210 | 0.80 | ADRB2 (0.52) | KMT2AALDH1A1POLBHPGDKDM4E | |
| SCHEMBL5308930 | 0.80 | MEN1 (0.53) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL14832179 | 0.79 | SPHK1 (0.47) | GAAALDH1A1RAB9ANPC1CA2 | |
| SCHEMBL854818 | 0.78 | L3MBTL1 (0.64) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL7794063 | 0.77 | MAPT (0.58) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL25095026 | 0.77 | TSHR (0.40) | MAPTL3MBTL1ALDH1A1ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059829-B2 | Rubber composition, tire, amine compound, and anti-aging agent | OTSUKA CHEMICAL CO., LTD. (JP) | 2018-08-28 | — | — | US | disclosed |
| EP-3147321-B1 | RUBBER COMPOSITION, TIRE, AMINE COMPOUND AND ANTI-AGING AGENT | OTSUKA CHEMICAL CO LTD (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-20170166727-A1 | RUBBER COMPOSITION, TIRE, AMINE COMPOUND, AND ANTI-AGING AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2017-06-15 | — | — | US | disclosed |
| US-20170166727-A1 | RUBBER COMPOSITION, TIRE, AMINE COMPOUND, AND ANTI-AGING AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2017-06-15 | — | — | US | disclosed |
| EP-3147321-A1 | RUBBER COMPOSITION, TIRE, AMINE COMPOUND AND ANTI-AGING AGENT | Otsuka Chemical Co., Ltd. (JP) | 2017-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166727-A1 | RUBBER COMPOSITION, TIRE, AMINE COMPOUND, AND ANTI-AGING AGENT | RAD54L, POT1, ATR | MEN1 2946/4885KMT2A 3339/4885MAPT 1637/4885 |
| US-10059829-B2 | Rubber composition, tire, amine compound, and anti-aging agent | RAD54L, POT1, ATR | MEN1 2946/4885KMT2A 3339/4885MAPT 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.