Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26759931 | 0.85 | MAPT (0.51) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL18641536 | 0.83 | LOXL2 (0.53) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL29065955 | 0.83 | HDAC1 (0.64) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL18641422 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL18667084 | 0.81 | KMT2A (0.47) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL18667131 | 0.79 | CYP11B1 (0.43) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL4500242 | 0.78 | AR (0.47) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL13680636 | 0.77 | MAPT (0.58) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL459230 | 0.76 | MAPT (0.54) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL18667301 | 0.76 | KDM4E (0.49) | ALDH1A1MAPTKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |