Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680636 | 0.83 | MAPT (0.58) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL18641536 | 0.80 | LOXL2 (0.53) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL26759931 | 0.79 | MAPT (0.51) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL7394802 | 0.78 | CA1 (0.56) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL7392985 | 0.77 | MMP2 (0.57) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL360517 | 0.77 | CSNK2A2 (0.67) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL18667203 | 0.76 | ALDH1A1 (0.49) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL15051048 | 0.76 | CSNK2A1 (0.68) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL4910418 | 0.76 | CDC7 (0.52) | MAPTKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL13801095 | 0.74 | KDM4E (0.68) | MAPTKDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615084-A1 | PROSTAGLANDIN D SYNTHASE INHIBITORY PIPERIDINE COMPOUNDS | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-07-17 | — | — | EP | disclosed |
| CN-103080086-A | Prostaglandin D synthase inhibitory piperidine compounds | TAIHO PHARMACEUTICAL CO LTD | 2013-05-01 | — | — | CN | disclosed |
| WO-2012033069-A1 | PROSTAGLANDIN D SYNTHASE INHIBITORY PIPERIDINE COMPOUNDS | 大鵬薬品工業株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |