Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19131686 | 0.96 | L3MBTL1 (0.37) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL23917170 | 0.96 | KDM4E (0.39) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL19131235 | 0.95 | L3MBTL1 (0.40) | KDM4EATML3MBTL1TSPOJAK2 | |
| SCHEMBL19844150 | 0.93 | KDM4E (0.35) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL19844142 | 0.91 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL20075327 | 0.91 | JAK2 (0.34) | KDM4EATML3MBTL1TSPOJAK2 | |
| SCHEMBL19132346 | 0.90 | L3MBTL1 (0.53) | KDM4EATML3MBTL1TSPOHDAC4 | |
| SCHEMBL24500383 | 0.89 | KDM4E (0.34) | KDM4EATML3MBTL1 | |
| SCHEMBL18668061 | 0.89 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL18668067 | 0.88 | KDM4E (0.47) | KDM4EATML3MBTL1HDAC4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421721-B2 | Heterocyclic compound and organic light emitting device comprising same | LG CHEM, LTD. (KR) | 2019-09-24 | — | — | US | disclosed |
| US-20180037547-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-02-08 | — | — | US | disclosed |
| US-20180037547-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-02-08 | — | — | US | disclosed |
| WO-2017047992-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2017-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421721-B2 | Heterocyclic compound and organic light emitting device comprising same | CRY1, CRY2, PER2 | KDM4E 2554/4885ATM 3310/4885L3MBTL1 856/4885 |
| US-20180037547-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CRY1, CRY2, PER2 | KDM4E 2554/4885ATM 3310/4885L3MBTL1 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.