Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | ADH5 | P11766 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244631 | 0.85 | CA12 (0.48) | ADH5CA12CA9MAOAMAOB | |
| SCHEMBL19244630 | 0.85 | ALDH5A1 (0.48) | ALDH1A1TRIM24TRIM33KCNJ1KDM4E | |
| SCHEMBL4549490 | 0.85 | HPGDS (0.50) | ALDH1A1ADH5KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6832118 | 0.85 | KCNJ1 (0.44) | ALDH1A1KCNJ1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL6758328 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1ADH5KDM4ESMN1; SMN2CA12 | |
| SCHEMBL16144601 | 0.84 | TPMT (0.50) | ALDH1A1ADH5KDM4ESMN1; SMN2CA12 | |
| SCHEMBL19244927 | 0.82 | KCNJ1 (0.45) | ALDH1A1TRIM24TRIM33KCNJ1KDM4E | |
| SCHEMBL4549492 | 0.82 | CYP2A6 (0.48) | ALDH1A1TRIM24TRIM33KCNJ1KDM4E | |
| SCHEMBL16030407 | 0.79 | KCNJ1 (0.42) | ALDH1A1KCNJ1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL19244926 | 0.79 | KCNJ1 (0.42) | ALDH1A1TRIM24TRIM33KCNJ1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604942-B2 | Preparation of haloalkoxyarylhydrazines and intermediates therefrom | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |